Allergic Bronchopulmonary Aspergillosis in Chronic Obstructive Pulmonary Disease
نویسنده
چکیده
Allergic bronchopulmonary aspergillosis (ABPA) is a most frequently recognised manifestation of pulmonary aspergillosis. Being an immunologically mediated disease, it usually occurs in atopic individuals and is caused by hypersensitivity reaction to aspergillus fumigatus. Patients with chronic obstructive pulmonary disease (COPD) have mucus hypersecretion and may favour occurrence of ABPA. However, ABPA is rarely reported in other lung disorders including COPD. Here we are reporting a case of COPD complicated by ABPA.
منابع مشابه
The emergence of Aspergillus species in chronic respiratory disease.
Chronic lung disease is recognized as an important risk factor for developing pulmonary aspergillosis. The development of specific aspergillus-associated syndromes depends on host immunity and underlying lung disease. In the setting of asthma, hypersensitivity to Aspergillus can lead to allergic bronchopulmonary aspergillosis (ABPA) or severe asthma with fungal sensitization (SAFS). Chronic use...
متن کاملChronic pulmonary aspergillosis: an update on diagnosis and treatment.
Chronic pulmonary aspergillosis (CPA) affects individuals with non-systemic or mildly systemic immunodepression or altered pulmonary integrity due to underlying disease. It has been reported with a variety of clinical and radiological patterns. The condition should be distinguished from simple aspergilloma and allergic bronchopulmonary aspergillosis as well as invasive aspergillosis in severely...
متن کاملCavitary Lung Lesions in a Difficult-To-Treat Asthma Patient.
We describe an interesting case of severe asthma who was not showing satisfactory response to standard treatment. Investigations revealed him to be suffering from allergic bronchopulmonary aspergillosis (ABPA). After starting systemic steroids he showed marked improvement initially only to have recurrent symptoms within a year. He was investigated further and found to have chronic pulmonary asp...
متن کاملImpact of Aspergillus fumigatus in allergic airway diseases
For decades, fungi have been recognized as associated with asthma and other reactive airway diseases. In contrast to type I-mediated allergies caused by pollen, fungi cause a large number of allergic diseases such as allergic bronchopulmonary mycoses, rhinitis, allergic sinusitis and hypersensitivity pneumonitis. Amongst the fungi, Aspergillus fumigatus is the most prevalent cause of severe pul...
متن کاملA snapshot of extracellular DNA influence on Aspergillus biofilm
ASPERGILLOSIS IN CLINICAL CONTEXT Aspergillosis is a fungal infection that can assume a broad spectrum of clinical forms depending on immune status and the presence of underlying lung diseases, ranging from allergic bronchopulmonary aspergillosis to aspergilloma and also to the invasive aspergillosis forms that are a major cause of mortality in severely immunocompromised patients. Pulmonary asp...
متن کامل